Handbooks and Manuals
Following are the handbooks and manuals we have that are useful for research in MCDB.
You will find books with Reference in front of the call number on the 2nd floor of the library in the reference section. Online resources are available on campus, or off-campus for current students, staff, and faculty.
Atlas of Mammalian Chromosomes
"A stunning visual collection of the banded metaphase chromosome karyotypes from some 850 species of mammals, the Atlas of Mammalian Chromosomes represents an unabridged compendium of the state of this genomic art form. Bringing together information currently scattered throughout the cytogenetics literature for scores of published and unpublished species, the atlas features high quality karyotype images for nearly every mammal studied to date, making it the most comprehensive assemblage of high resolution chromosome photographs available, a critically invaluable resource for todays comparative genomics era. For every available species, the atlas presents the best karyotype produced, the common and Latin name of the species, the published citation, and the contributing authors. Nearly all karyotypes are G banded, revealing the chromosomal bar codes of homologous segments among related species. Addressing the mandate of the Human Genome Project to annotate the genomes of other organisms as well, this edition offers a step forward in our understanding of species formation, of genome organization, and of DNA script for natural selection. It is an invaluable resource for geneticists, mammalogists, and biologists interested in comparative genomics, systematics, and chromosome structure. The book will include karyotypes of 1000 of the 5000 species of mammals. These images provide the starting point for a new dynamic field called "ComparativeGenomics" which is driven by the whole genome sequence discernment of biological species. When the atlas was first published, only three mammals were sequenced (human, mouse and rat). Today nearly 300 non-human mammal species enjoy genome sequence empowerment. This practice has become mainstream rigor, with genome sequencing being planed for nearly all mammal species in the coming decade. Updating the atlas will ignite the starting point for so many of these exciting new research endeavors"
Call Number: (Electronic Resource)Publication Date: 2020
Biochemistry and Molecular Biology Compendium
This book is an accessible resource offering practical information not found in more database-oriented resources. The first chapter lists acronyms with definitions, and a glossary of terms and subjects used in biochemistry, molecular biology, biotechnology, proteomics, genomics, and systems biology. There follows chapters on chemicals employed in biochemistry and molecular biology, complete with properties and structure drawings. Researchers will find this book to be a valuable tool that will save them time, as well as provide essential links to the roots of their science. Key selling features: Contains an extensive list of commonly used acronyms with definitions Offers a highly readable glossary for systems and techniques Provides comprehensive information for the validation of biotechnology assays and manufacturing processes Includes a list of Log P values, water solubility, and molecular weight for selected chemicals Gives a detailed listing of protease inhibitors and cocktails, as well as a list of buffers
Call Number: (Electronic Resource)Publication Date: 2019
Color Atlas of Genetics
Ever since the international Human Genome Project achieved its extraordinary goal of sequencing and mapping the entire human genome--with far-reaching implications for understanding the causes and diagnosis of human genetic disorders--progress in the field has been rapid. In the fourth edition of the bestselling Color Atlas of Genetics, readers will get a full overview of the field today, with an emphasis on the interface between fundamental principles and practical applications in medicine. The book utilizes the signature Flexibook format designed for easy visual learning and retention, and is invaluable for students, clinicians, and scientists interested in keeping current in this fast-moving area. New topics in the fully revised fourth edition of this highly praised atlas: Genetic signaling pathways involved in genetic disorders DNA repair systems Genomic disorders and genome-wide association studies Cancer genomes Ciliopathies, neurocristopathies, and other groups of causally related disorders Epigenetic changes in certain disorders Illustrated outline of human evolution With almost 200 stunning color plates concisely explained on facing pages, and including useful tables of data, a glossary of terms, key references, and online resources, this book makes every concept clear and accessible. It is an excellent introduction to genetics and basic genomics for students of medicine and biology, as well as an ideal teaching aid and refresher for investigators in any field of medicine or science.
Call Number: Reference QH436 .P3713 2013 (Print Resource)Publication Date: 2012
Comprehensive Physiology
"Comprehensive Physiology is the most authoritative and comprehensive collection of physiology information that has ever been assembled. Its starting point is more than 30,000 pages of content from the American Physiological Society's renowned Handbook of Physiology (HoP) series, which is presented here for the first time in an online format. With the launch of Comprehensive Physiology in January 2011, we will begin publishing regular issues that update and expand the classic content from HoP, as well as adding fresh review material. In this way, we aim to capture the full breadth and depth of the evolving science of physiology. New and updated materials will be published in a quarterly serial format ... The primary audience for Comprehensive Physiology is academic scientists in the life sciences. Secondary audiences include advanced students in the life sciences and medicine, instructors in these disciplines, and academic clinicians"
Call Number: (Electronic Resource)Publication Date: Current Subscription
Comprehensive Toxicology
An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version
Call Number: (Electronic Resource)Publication Date: 2010
Data Science Handbook: A Practical Approach
DATA SCIENCE HANDBOOK This desk reference handbook gives a hands-on experience on various algorithms and popular techniques used in real-time in data science to all researchers working in various domains. Data Science is one of the leading research-driven areas in the modern era. It is having a critical role in healthcare, engineering, education, mechatronics, and medical robotics. Building models and working with data is not value-neutral. We choose the problems with which we work, make assumptions in these models, and decide on metrics and algorithms for the problems. The data scientist identifies the problem which can be solved with data and expert tools of modeling and coding. The book starts with introductory concepts in data science like data munging, data preparation, and transforming data. Chapter 2 discusses data visualization, drawing various plots and histograms. Chapter 3 covers mathematics and statistics for data science. Chapter 4 mainly focuses on machine learning algorithms in data science. Chapter 5 comprises of outlier analysis and DBSCAN algorithm. Chapter 6 focuses on clustering. Chapter 7 discusses network analysis. Chapter 8 mainly focuses on regression and naive-bayes classifier. Chapter 9 covers web-based data visualizations with Plotly. Chapter 10 discusses web scraping. The book concludes with a section discussing 19 projects on various subjects in data science. Audience The handbook will be used by graduate students up to research scholars in computer science and electrical engineering as well as industry professionals in a range of industries such as healthcare.
Call Number: (Electronic Resource)Publication Date: 2022
Digital Qualitative Research Methods
The field of digital methods for qualitative research is a rapidly developing one. More and more researchers are researching the social, cultural, political, anthropological and other dimensions of computer-mediated communication (CMC), or using CMC as a means of generating and analysing research data. There is now a proliferating diversity of terms, including digital methods, online methods, virtual ethnography, hypermedia methods, and so forth, that requires clarification and classification. This four-volume set brings together the most important and influential articles that have been published in this area and which enable the reader to understand the implications of digital technology for all aspects and phases of qualitative research design and dissemination.
Call Number: Reference Q180.55.E4 D54 2012 (Print Resource)Publication Date: 2012
Efficiency in Natural Product Total Synthesis
Uniting the key organic topics of total synthesis and efficient synthetic methodologies, this book clearly overviews synthetic strategies and tactics applied in total synthesis, demonstrating how the total synthesis of natural products enables scientific and drug discovery. * Focuses on efficiency, a fundamental and important issue in natural products synthesis that makes natural product synthesis a powerful tool in biological and pharmaceutical science * Describes new methods like organocatalysis, multicomponent and cascade reactions, and biomimetic synthesis * Appeals to graduate students with two sections at the end of each chapter illustrating key reactions, strategies, tactics, and concepts; and good but unfinished total synthesis (synthesis of core structure) before the last section * Compiles examples of solid phase synthesis and continuing flow chemistry-based total synthesis which are very relevant and attractive to industry R&D professionals
Call Number: (Electronic Resource)Publication Date: 2018
Fundamentals of Fluorescence Imaging
Fluorescence imaging, at macro, micro, and submicro scales, has revolutionized biological science in the past 30 years. Immunolabelling has provided precise targeting of molecules in fixed tissue, while fluorescent proteins have enabled localization in living tissues. Fluorescent indicators enable imaging of dynamic changes in cell metabolism. This book covers, for the first time, imaging at all scales from macro to submicro (superresolution). Its authors include Robert Clegg, legendary teacher and researcher (who, sadly, passed away during the editing); Jim Pawley, editor of several editions of the Handbook of Biological Confocal Microscopy; the famous and now dispersed New Zealand team of Mark Cannell, Christian Soeller, and David Baddeley; Robert Hoffman, pioneer of whole-animal imaging in cancer research; Andreas Schoenle and Christian Eggeling on STED nanoscopy, and many more famous participants in this field. All the contributors are at the cutting edge of their field.
Call Number: (Electronic Resource)Publication Date: 2019
Handbook of Behavior Genetics
This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.
Call Number: (Electronic Resource)Publication Date: 2009
Handbook of Biochemistry and Molecular Biology
Edited by renowned protein scientist and bestselling author Roger L. Lundblad, with the assistance of Fiona M. Macdonald of CRC Press, this fifth edition of the　Handbook of Biochemistry and Molecular Biology　gathers a wealth of information not easily obtained, including information not found on the web. Presented in an organized, concise, and simple-to-use format, this popular reference allows quick access to the most frequently used data. Covering a wide range of topics, from classical biochemistry to proteomics and genomics, it also details the properties of commonly used biochemicals, laboratory solvents, and reagents. An entirely new section on Chemical Biology and Drug Design gathers data on amino acid antagonists, click chemistry, plus glossaries for computational drug design and medicinal chemistry. Each table is exhaustively referenced, giving the user a quick entry point into the primary literature. New tables for this edition: Chromatographic methods and solvents Protein spectroscopy Partial volumes of amino acids Matrix Metalloproteinases Gene Editing Click Chemistry
Call Number: (Electronic Resource)Publication Date: 2018
Handbook of Biological Confocal Microscopy
Once the second edition was safely off to the printer, the 110 larger world of micro-CT and micro-MRI and the smaller world authors breathed a sigh of relief and relaxed, secure in the belief revealed by the scanning and transmission electron microscopes. that they would "never have to do that again. " That lasted for 10 To round out the story we even have a chapter on what PowerPoint years. When we ?nally awoke, it seemed that a lot had happened. does to the results, and the annotated bibliography has been In particular, people were trying to use the Handbook as a text- updated and extended. book even though it lacked the practical chapters needed. There As with the previous editions, the editor enjoyed a tremendous had been tremendous progress in lasers and ?ber-optics and in our amount of good will and cooperation from the 124 authors understanding of the mechanisms underlying photobleaching and involved. Both I, and the light microscopy community in general, phototoxicity. It was time for a new book. I contacted "the usual owe them all a great debt of gratitude. On a more personal note, I suspects" and almost all agreed as long as the deadline was still a would like to thank Kathy Lyons and her associates at Springer for year away.
Call Number: QH224 .H36 2006 (Print and Electronic Resource)Publication Date: 2006
Handbook of Biologically Active Peptides
Handbook of Biologically Active Peptides, Second Edition, is the definitive, indispensable reference for peptide researchers, biochemists, cell and molecular biologists, neuroscientists, pharmacologists, and endocrinologists. Its chapters are designed to be a source for workers in the field and enable researchers working in a specific area to examine related areas outside their expertise. Peptides play a crucial role in many physiological processes, including actions as neurotransmitters, hormones, and antibiotics. Research has shown their importance in such fields as neuroscience, immunology, pharmacology, and cell biology. The second edition of Handbook of Biologically Active Peptides presents this tremendous body of knowledge in the field of biologically active peptides in one single reference. The section editors and contributors represent some of the most sophisticated and distinguished scientists working in basic sciences and clinical medicine. Presents all aspects of biologically active peptides in one resource Features more than 20 sections spanning plant, bacterial, fungal, venom, and invertebrate peptides to general peptides Includes immunological, inflammatory, cancer, vaccine, and neurotrophic peptides Discusses peptide precursors, mRNA distribution, processing, and receptors, not just pathophysiological implications
Call Number: (Electronic Resource)Publication Date: 2013
Handbook of Computational Molecular Biology
The enormous complexity of biological systems at the molecular level must be answered with powerful computational methods. Computational biology is a young field, but has seen rapid growth and advancement over the past few decades. Surveying the progress made in this multidisciplinary field, the Handbook of Computational Molecular Biology offers comprehensive, systematic coverage of the various techniques and methodologies currently available. Accomplished researcher Srinivas Aluru leads a team of experts from around the world to produce this groundbreaking, authoritative reference. With discussions ranging from fundamental concepts to practical applications, this book details the algorithms necessary to solve novel problems and manage the massive amounts of data housed in biological databases throughout the world. Divided into eight sections for convenient searching, the handbook covers methods and algorithms for sequence alignment, string data structures, sequence assembly and clustering, genome-scale computational methods in comparative genomics, evolutionary and phylogenetic trees, microarrays and gene expression analysis, computational methods in structural biology, and bioinformatics databases and data mining. The Handbook of Computational Molecular Biology is the first resource to integrate coverage of the broad spectrum of topics in computational biology and bioinformatics. It supplies a quick-reference guide for easy implementation and provides a strong foundation for future discoveries in the field.
Call Number: QH324.2 .H357 2006 (Print and Electronic Resource)Publication Date: 2005
Handbook of Developmental Science, Behavior, and Genetics
The Handbook of Developmental Science, Behavior, and Genetics brings together the cutting-edge theory, research and methodology that contribute to our current scientific understanding of the role of genetics in the developmental system. * Commemorates the historically important contributions made by Gilbert Gottlieb in comparative psychology and developmental science * Includes an international group of contributors who are among the most respected behavioral and biological scientists working today * Examines the scientific basis for rejecting the reductionism and counterfactual approach to understanding the links between genes, behavior, and development * Documents the current status of comparative psychology and developmental science and provides the foundation for future scientific progress in the field
Call Number: (Electronic Resource)Publication Date: 2010
Handbook of Molecular and Cellular Methods in Biology and Medicine
Several milestones in biology have been achieved since the first publication of the Handbook of Molecular and Cellular Methods in Biology and Medicine. This is true particularly with respect to genome-level sequencing of higher eukaryotes, the invention of DNA microarray technology, advances in bioinformatics, and the development of RNAi technology. Now in its third edition, this volume provides researchers with an updated tool kit that incorporates conventional as well as modern approaches to tackle biological and medicinal research in the post-genomics era. Significantly revised to address these recent changes, the editors have evaluated, revised, and sometimes replaced protocols with more efficient, more reliable, or simpler ones. The book has also been reorganized with section headings focusing on different biological levels connected to one another, taking into account the central dogma of biology (DNA → RNA → protein → metabolites). The book first explores traditional approaches and then moves to the modern "omics" approaches, including genomics, proteomics, and metabolomics. It also discusses the manipulation of biological systems (including RNAi) and macromolecular analyses, focusing on the use of microscopy. In each chapter, various notes and cautionary considerations are presented for potentially hazardous reagents. Filled with diagrams, tables, and figures to clarify methods, most chapters also contain Troubleshooting Guides indicating problems, possible causes, and solutions that may be incurred in carrying out the procedures. Researchers and scientists who master the techniques in this book are putting themselves at the cutting edge of biological and medicinal research.
Call Number: Reference QH506 .H36 2012 (Print Resource)Publication Date: 2011
Handbook of Neurochemistry and Molecular Neurobiology: Brain Energetics. Integration of Molecular and Cellular Processes
BIOENERGETICS - D. G. Nicholls.- GLUCOSE, OXIDATIVE ENERGY METABOLISM, AND NEURAL FUNCTION IN BRAIN SLICES - GLYCOLYSIS PLAYS A KEY ROLE IN NEURAL ACTIVITY - Y. Okada, P. Lipton.- PENTOSE PHOSPHATE PATHWAY AND NADPH METABOLISM - R. Dringen, H. H. Hoepken, T. Minich, and C. Ruedig.- THE CEREBRAL TRICARBOXYLIC ACID CYCLES - T. B. Rodrigues and S. Cerdán.- ELECTRON TRANSPORT: STRUCTURE, REDOX-COUPLED PROTONMOTIVE ACTIVITY, AND PATHOLOGICAL DISORDERS OF RESPIRATORY CHAIN COMPLEXES - S. Papa, V. Petruzzella, and S. Scacco.- THE MITOCHONDRIAL F1F0 ATP SYNTHASE - A. Gaballo and S. Papa.- THE SUPPORT OF ENERGY METABOLISM IN THE CENTRAL NERVOUS SYSTEM WITH SUBSTRATES OTHER THAN GLUCOSE - E. L. Roberts, Jr.- ANAPLEROSIS - B. Hassel.- GLIAL-NEURONAL SHUTTLE SYSTEMS - C. Zwingmann and D. Leibfritz.- CYTOPLASMIC GLYCOLYTIC ENZYMES. SYNAPTIC VESICLE-ASSOCIATED GLYCOLYTIC ATP-GENERATING ENZYMES: COUPLING TO NEUROTRANSMITTER ACCUMULATION - T. Ueda and A. Ikemoto.- MITOCHONDRIAL ARCHITECTURE AND HETEROGENEITY - G. A. Perkins and M. H. Ellisman.- COUPLING OF NEURONAL FUNCTION TO OXYGEN AND GLYCOSE METABOLISM THROUGH CHANGES IN NEUROTRANSMITTER DYNAMICS AS REVEALED WITH AGING, HYPOGLYCEMIA AND HYPOXIA - J. A. Joseph and G. E. Gibson.- COUPLING OF BRAIN FUNCTION AND METABOLISM: ENDOGENOUS FLAVOPROTEIN FLUORESCENCE IMAGING OF NEURAL ACTIVITIES BY LOCAL CHANGES IN ENERGY METABOLISM - K. Shibuki, R. Hishida, H. Kitaura, K, Takahashi, and M. Tohmi.- COUPLING OF BRAIN FUNCTION TO METABOLISM: EVALUATION OF ENERGY REQUIREMENTS - A. Gjedde.- ENERGY CONSUMPTION BY PHOSPHOLIPID METABOLISM IN MAMMALIAN BRAIN - A. D. Purdon and S. I. Rapoport.- ION TRANSPORT AND ENERGY METABOLISM - O. Vergun, K. E. Dineley, and I. J. Reynolds.- ACID-BASE TRANSPORT AND pH REGULATION - J. W. Deitmer.- NITRIC OXIDE IN REGULATION OF MITOCHONDRIAL FUNCTION, RESPIRATION, AND GLYCOLYSIS - J. P. Bolaños and A. Almeida.- MITOCHONDRIAL PRODUCTION OF OXIDANTS AND THEIR ROLE IN THE REGULATION OF CELLULAR PROCESSES - P. S. Brookes.- UNCOUPLING PROTEINS - J. S. Kim-Han, S. S. Ali, and L. L. Dugan.- ACTIONS OF TOXINS ON CEREBRAL METABOLISM AT THE CELLULAR LEVEL - U. Sonnewald, T. Syversen, A. Schousboe, H. Waagepetersen, and M. Aschner.- MITOCHONDRIAL/CYTOSOLIC INTERACTIONS VIA METABOLITE SHUTTLES AND TRANSPORTERS - K. F. LaNoue, V. Carson, D.A. Berkich, and S. M. Hutson.- MITOCHONDRIAL-ENDOPLASMIC RETICULUM INTERACTIONS - G. Szabadkai and R. Rizzuto.- MITOCHONRIA-NUCLEUS ENERGETIC COMMUNICATION: ROLE FOR PHOSPHOTRANSFER NETWORKS IN PROCESSING CELLULAR INFORMATION - P. P. Dzeja and A. Terzic.- MITOCHONDRIAL PERMEABILITY TRANSITION IN THE CNS - COMPOSITION, REGULATION, AND PATHOPHYSIOLOGICAL RELEVANCE- T. Wieloch, G. Mattiasson, M. J. Hansson, and E. Elmér.- MITOCHONDRIAL MECHANISMS OF OXIDATIVE STRESS AND APOPTOSIS - L. Soane, N. Solenski, G. Fiskum.- PROTEOMICS - M. H. Maurer and W. Kuschinsky.- GENETICS AND GENE EXPRESSION OF GLYCOLYSIS - J. C. LaManna, P. Pichiule, and J. C. Chavez.- TRANSCRIPTIONAL INTEGRATION OF MITOCHONDRIAL BIOGENESIS - R. C. Scarpulla.- MECHANISMS AND MODELING OF ENERGY TRANSFER BETWEEN INTRACELLULAR COMPARTMENTS - V. A. Saks, M. Vendelin, M. K. Aliev, T. Kekelidze, and J. Engelbrecht.- MODELING OF REGULATION OF GLYCOLYSIS AND OVERALL ENERGY METABOLISM UNDER A SYSTEMS BIOLOGY APPROACH - M. Cascante, L. G. Boros, and J. Boren.- MODELING OF ELECTRON TRANSPORT: IMPLICATIONS TO MITOCHONDRIAL DISEASES - J-P. Mazat, M. Beurton-Aimar, B. Faustin, T. Letellier, M. Malgat, C. Nazaret, and R. Rossignol.- METABOLOMICS: CONCEPTS AND POTENTIAL NEUROSCIENCE APPLICATIONS - B. S. Kristal, R. Kaddurah-Daouk, M. F. Beal, and W. R. Matson
Call Number: (Electronic Resource)Publication Date: 2007
Handbook of Neurochemistry and Molecular Neurobiology: Practical Neurochemistry Methods
The Handbook is intended to be a service to the neuroscience community, to help in finding available and useful information, to point out gaps in our knowledge, and to encourage continued studies. It represents the valuable contributions of the many authors of the chapters and the guidance of the editors and most important, it represents support for research in this discipline. Based on the rapid advances in the years since the second edition
Call Number: (Electronic Resource)Publication Date: 2007
Handbook of Plant Biotechnology
This important reference is the first work on Plant Biotechnology. Written by an international team of experienced researchers and professionals from both academia and industry, it will bring together the principles and practice of contemporary plant biotechnology to include: * the techniques of plant genetic modification - applications of plant biotechnology, crop improvement in agriculture and a production system for pharmaceutical proteins * ethics and safety issues - public perception, public relations, scale-up and testing, and legislation within the business of plant biotechnology.
Call Number: TP248.27.P55 C545 2004 (Print and Electronic Resource)Publication Date: 2004
The Handbook of Research Synthesis and Meta-Analysis
Research synthesis is the practice of systematically distilling and integrating data from many studies in order to draw more reliable conclusions about a given research issue. When the first edition of The Handbook of Research Synthesis and Meta-Analysis was published in 1994, it quickly became the definitive reference for conducting meta-analyses in both the social and behavioral sciences. In the third edition, editors Harris Cooper, Larry Hedges, and Jeff Valentine present updated versions of classic chapters and add new sections that evaluate cutting-edge developments in the field. The Handbook of Research Synthesis and Meta-Analysis draws upon groundbreaking advances that have transformed research synthesis from a narrative craft into an important scientific process in its own right. The editors and leading scholars guide the reader through every stage of the research synthesis process--problem formulation, literature search and evaluation, statistical integration, and report preparation. The Handbook incorporates state-of-the-art techniques from all quantitative synthesis traditions and distills a vast literature to explain the most effective solutions to the problems of quantitative data integration. Among the statistical issues addressed are the synthesis of non-independent data sets, fixed and random effects methods, the performance of sensitivity analyses and model assessments, the development of machine-based abstract screening, the increased use of meta-regression and the problems of missing data. The Handbook also addresses the non-statistical aspects of research synthesis, including searching the literature and developing schemes for gathering information from study reports. Those engaged in research synthesis will find useful advice on how tables, graphs, and narration can foster communication of the results of research syntheses. The third edition of the Handbook provides comprehensive instruction in the skills necessary to conduct research syntheses and represents the premier text on research synthesis. Praise for the first edition: "The Handbook is a comprehensive treatment of literature synthesis and provides practical advice for anyone deep in the throes of, just teetering on the brink of, or attempting to decipher a meta-analysis. Given the expanding application and importance of literature synthesis, understanding both its strengths and weaknesses is essential for its practitioners and consumers. This volume is a good beginning for those who wish to gain that understanding." --Chance "Meta-analysis, as the statistical analysis of a large collection of results from individual studies is called, has now achieved a status of respectability in medicine. This respectability, when combined with the slight hint of mystique that sometimes surrounds meta-analysis, ensures that results of studies that use it are treated with the respect they deserve....The Handbook of Research Synthesis is one of the most important publications in this subject both as a definitive reference book and a practical manual."--British Medical Journal When the first edition of The Handbook of Research Synthesis was published in 1994, it quickly became the definitive reference for researchers conducting meta-analyses of existing research in both the social and biological sciences. In this fully revised second edition, editors Harris Cooper, Larry Hedges, and Jeff Valentine present updated versions of the Handbook''s classic chapters, as well as entirely new sections reporting on the most recent, cutting-edge developments in the field. Research synthesis is the practice of systematically distilling and integrating data from a variety of sources in order to draw more reliable conclusions about a given question or topic. The Handbook of Research Synthesis and Meta-Analysis draws upon years of groundbreaking advances that have transformed research synthesis from a narrative craft into an important scientific process in its own right. Cooper, Hedges, and Valentine have assembled leading authorities in the field to guide the reader through every stage of the research synthesis process--problem formulation, literature search and evaluation, statistical integration, and report preparation. The Handbook of Research Synthesis and Meta-Analysis incorporates state-of-the-art techniques from all quantitative synthesis traditions. Distilling a vast technical literature and many informal sources, the Handbook provides a portfolio of the most effective solutions to the problems of quantitative data integration. Among the statistical issues addressed by the authors are the synthesis of non-independent data sets, fixed and random effects methods, the performance of sensitivity analyses and model assessments, and the problem of missing data. The Handbook of Research Synthesis and Meta-Analysis also provides a rich treatment of the non-statistical aspects of research synthesis. Topics include searching the literature, and developing schemes for gathering information from study reports. Those engaged in research synthesis will also find useful advice on how tables, graphs, and narration can be used to provide the most meaningful communication of the results of research synthesis. In addition, the editors address the potentials and limitations of research synthesis, and its future directions. The past decade has been a period of enormous growth in the field of research synthesis. The second edition Handbook thoroughly revises original chapters to assure that the volume remains the most authoritative source of information for researchers undertaking meta-analysis today. In response to the increasing use of research synthesis in the formation of public policy, the second edition includes a new chapter on both the strengths and limitations of research synthesis in policy debates
Call Number: (Electronic Resource)Publication Date: 2019
Handbook of Statistical Genetics
The Handbook for Statistical Genetics is widely regarded as the reference work in the field. However, the field has developed considerably over the past three years. In particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. As a consequence the 3rd edition of the handbook contains a much expanded section on Network Modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. Other chapters new to the 3rd edition include Human Population Genetics, Genome-wide Association Studies, Family-based Association Studies, Pharmacogenetics, Epigenetics, Ethic and Insurance. As with the second Edition, the Handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. With heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research. Edited by the leading international authorities in the field. David Balding - Department of Epidemiology & Public Health, Imperial College An advisor for our Probability & Statistics series, Professor Balding is also a previous Wiley author, having written Weight-of-Evidence for Forensic DNA Profiles, as well as having edited the two previous editions of HSG. With over 20 years teaching experience, he's also had dozens of articles published in numerous international journals. Martin Bishop - Head of the Bioinformatics Division at the HGMP Resource Centre As well as the first two editions of HSG, Dr Bishop has edited a number of introductory books on the application of informatics to molecular biology and genetics. He is the Associate Editor of the journal Bioinformatics and Managing Editor of Briefings in Bioinformatics. Chris Cannings - Division of Genomic Medicine, University of Sheffield With over 40 years teaching in the area, Professor Cannings has published over 100 papers and is on the editorial board of many related journals. Co-editor of the two previous editions of HSG, he also authored a book on this topic.
Call Number: Reference QH438.4.S73 H36 2007 (Print Resource)Publication Date: 2007
Handbook of Statistical Genomics
A timely update of a highly popular handbook on statistical genomics This new, two-volume edition of a classic text provides a thorough introduction to statistical genomics, a vital resource for advanced graduate students, early-career researchers and new entrants to the field. It introduces new and updated information on developments that have occurred since the 3rd edition. Widely regarded as the reference work in the field, it features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It expands on previous coverage of the many processes between genotype and phenotype, including gene expression and epigenetics, as well as metabolomics. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. The Handbook of Statistical Genomics focuses on explaining the main ideas, analysis methods and algorithms, citing key recent and historic literature for further details and references. It also includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between chapters, tying the different areas together. With heavy use of up-to-date examples and references to web-based resources, this continues to be a must-have reference in a vital area of research. Provides much-needed, timely coverage of new developments in this expanding area of study Numerous, brand new chapters, for example covering bacterial genomics, microbiome and metagenomics Detailed coverage of application areas, with chapters on plant breeding, conservation and forensic genetics Extensive coverage of human genetic epidemiology, including ethical aspects Edited by one of the leading experts in the field along with rising stars as his co-editors Chapter authors are world-renowned experts in the field, and newly emerging leaders. The Handbook of Statistical Genomics is an excellent introductory text for advanced graduate students and early-career researchers involved in statistical genetics.
Call Number: (Electronic Resource)Publication Date: 2019
Handbook of Statistical Systems Biology
Systems Biology is now entering a mature phase in which the key issues are characterising uncertainty and stochastic effects in mathematical models of biological systems. The area is moving towards a full statistical analysis and probabilistic reasoning over the inferences that can be made from mathematical models. This handbook presents a comprehensive guide to the discipline for practitioners and educators, in providing a full and detailed treatment of these important and emerging subjects. Leading experts in systems biology and statistics have come together to provide insight in to the major ideas in the field, and in particular methods of specifying and fitting models, and estimating the unknown parameters. This book: Provides a comprehensive account of inference techniques in systems biology. Introduces classical and Bayesian statistical methods for complex systems. Explores networks and graphical modeling as well as a wide range of statistical models for dynamical systems. Discusses various applications for statistical systems biology, such as gene regulation and signal transduction. Features statistical data analysis on numerous technologies, including metabolic and transcriptomic technologies. Presents an in-depth presentation of reverse engineering approaches. Provides colour illustrations to explain key concepts. This handbook will be a key resource for researchers practising systems biology, and those requiring a comprehensive overview of this important field.
Call Number: (Electronic Resource)Publication Date: 2011
Handbook of Stem Cells
New discoveries in the field of stem cells increasingly dominate the news and scientific literature revealing an avalanche of new knowledge and research tools that are producing therapies for cancer, heart disease, diabetes, and a wide variety of other diseases that afflict humanity. The Handbook of Stem Cells integrates this exciting area of life science, combining in two volumes the requisites for a general understanding of adult and embryonic stem cells. Organized in two volumes entitled Pluripotent Stem Cells and Cell Biology and Adult and Fetal Stem Cells, this work contains contributions from the world's experts in stem cell research to provide a description of the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations as well as a the latest information of what is known about each specific organ system.
Call Number: (Electronic Resource)Publication Date: 2012
Handbook of Toxicology
The Handbook of Toxicology, Third Edition provides an updated practical reference source for practicing toxicologists in the pharmaceutical and chemical industries, contract laboratories, regulatory agencies, and academia. Written by experts in their specific toxicology fields, the chapters provide both fundamental and applied information. Topics r
Call Number: (Electronic Resource)Publication Date: 2014
The Merck Index
The Merck Index is a one-volume encyclopedia of chemicals, drugs and biologicals that contains more than 10,000 monographs. Each monograph in this authoritative reference source is a concise description of a single substance or a small group of closely related compounds. Compounds included: - human and veterinary drugs - biotech drugs and monoclonal antibodies - substances used for medical imaging - biologicals and natural products - plants and traditional medicines - nutraceuticals and cosmeceuticals - agriculturals, pesticides and herbicides - Organic chemicals used in research - Food additives and supplements - dyes, colors and indicators - environmentally significant substances Information provided: - chemical, common and generic names - Over 15,000 trademarks and associated companies - CAS Registry Numbers for over 12,000 compounds - Over 8,500 chemical structures - molecular formulae, weights and percentage composition - capsule statements identifying compound classes and scientific significance - scientific and patent literature references - physical and toxicity data - therapeutic and commercial uses - caution and hazard information In addition, there are more than 700 new and completely revised monographs, thousands of new references, trademarks and uses added to existing monographs. Now includes a companion CD-ROM which features 989 monographs no longer available in print, organic name reactions, supplemental tables and a new user interface for user-friendly searching. Features of the CD: Searchable by keywords, references, and numerical properties Search the complete contents of the 14th edition, plus nearly a thousand monographs archived from previous editions Comes with a free one-year subscription to the Merck Index Internet Edition Windows-compatible CD powered by CambridgeSoft's ChemFinder Extensively revised supplemental tables now including acronyms, vaccines, and physical constants More than 70 pages of hard to find information in one easy-to-use place
Call Number: (Electronic Resource)Publication Date: 2021-
Molecular Biomethods Handbook
Recent advances in the biosciences have led to a range of powerful new technologies, particularly nucleic acid, protein and cell-based methodologies. The most recent insights have come to affect how scientists investigate and define cellular processes at the molecular level. This book expands upon the techniques included in the first edition, providing theory, outlines of practical procedures, and applications for a range of techniques. Written by a well-established panel of research scientists, the book provides an up-to-date collection of methods used regularly in the authors' own research programs.
Call Number: (Electronic Resource)Publication Date: 2008
The Pharmacological Basis of Therapeutics
The landmark text in medical pharmacology is now in full color Includes DVD with image bank A Doody's Core Title for 2017! 4 STAR DOODY'S REVIEW! "This 12th edition of the most authoritative book in pharmacology is the best both in content and physical appearance....This edition of Goodman & Gilman's continues to be the most authoritative and widely used resource bridging the discipline of pharmacology with therapeutics. Moreover, readers will find this edition to be substantially improved from past editions in both content and physical appearance."--Doody's Review Service The most universally respected and read medical text in all of pharmacology, Goodman & Gilman's The Pharmacological Basis of Therapeutics represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilman's careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease. Enriched by a new full-color presentation and updated to reflect all critical new developments in drug action and drug-disease interaction, the twelfth edition includes more than 440 color illustrations depicting key principles and actions of specific pathways and therapeutic agents. The companion DVD includes all the images and tables in the text along with narrated animations. Goodman & Gilman's The Pharmacological Basis of Therapeutics, 12e is divided into nine sections, covering: General Principles Neuropharmacology Modulation of Cardiovascular Function Inflammation, Immunomodulation, and Hematopoiesis Endocrine Pharmacology Gastrointestinal Pharmacology Chemotherapy of Infectious Disease Chemotherapy of Neoplastic Diseases Special Systems Pharmacology More than a textbook, Goodman & Gilman's is a working template for the effective and rational prescribing of drugs in daily practice.
Call Number: Reference RM300 .G644 2011 (Print Resource)Publication Date: 2011
Plant Cell and Tissue Culture: A Tool in Biotechnology
This book provides a general introduction as well as a selected survey of key advances in the fascinating field of plant cell and tissue culture as a tool in biotechnology. After a detailed description of the various basic techniques employed in leading laboratories worldwide, follows an extended account of important applications in, for example, plant propagation, secondary metabolite production and gene technology. Additionally, some chapters are devoted to historical developments in this domain, metabolic aspects, nutrition, growth regulators, differentiation and the development of culture systems. The book will prove useful to both newcomers and specialists, and even "old hands" in tissue culture should find some challenging ideas to think about.
Call Number: (Electronic Resource)Publication Date: 2009
Research Data Management and Data Literacies
Research Data Management and Data Literacies help researchers familiarize themselves with RDM, and with the services increasingly offered by libraries. This new volume looks at data-intensive science, or 'Science 2.0' as it is sometimes termed in commentary, from a number of perspectives, including the tasks academic libraries need to fulfil, new services that will come online in the near future, data literacy and its relation to other literacies, research support and the need to connect researchers across the academy, and other key issues, such as 'data deluge,' the importance of citations, metadata and data repositories. This book presents a solid resource that contextualizes RDM, including good theory and practice for researchers and professionals who find themselves tasked with managing research data. Gives guidance on organizing, storing, preserving and sharing research data using Research Data Management (RDM) Contextualizes RDM within the global shift to data-intensive research Helps researchers and information professionals understand and optimize data-intensive ways of working Considers RDM in relation to varying needs of researchers across the sciences and humanities Presents key issues surrounding RDM, including data literacy, citations, metadata and data repositories
Call Number: (Electronic Resource)Publication Date: 2021
Springer Handbook of Enzymes
The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized - and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.
Call Number: (Electronic Resource) - Search within UC Library Search for specific volumePublication Date: 2007
Stem Cells Handbook
This book discusses critical areas of progress in stem cell research, including the most recent research and applications of pluripotent embryonic cells, induced pluripotent cells, oligopotent tissue stem cells and cancer stem cells. The text covers basic knowledge of stem cell biology, stem cell ethics, development of techniques for applying stem cell therapy, the technology of obtaining appropriate cells for transplantation as well as the role of stem cells in cancer and how therapy may be directed to cancer stem cells. This new volume is essential reading for all scientists currently in the field or allied research areas, and those for those graduate students who envision a career in stem cells.nbsp;
Call Number: (Electronic Resource)Publication Date: 2013
Stereoselective Synthesis of Drugs and Natural Products
Brings together the best tested and proven stereoselective synthetic methods Both the chemical and pharmaceutical industries are increasingly dependent on stereoselective synthetic methods and strategies for the generation of new chiral drugs and natural products that offer specific 3-D structures. With the publication of Stereoselective Synthesis of Drugs and Natural Products, researchers can turn to this comprehensive two-volume work to guide them through all the core methods for the synthesis of chiral drugs and natural products. Stereoselective Synthesis of Drugs and Natural Products features contributions from an international team of synthetic chemists and pharmaceutical and natural product researchers. These authors have reviewed the tremendous body of literature in the field in order to compile a set of reliable, tested, and proven methods alongside step-by-step guidance. This practical resource not only explores synthetic methodology, but also reaction mechanisms and applications in medicinal chemistry and drug discovery. The publication begins with an introductory chapter covering general principles and methodologies, nomenclature, and strategies of stereoselective synthesis. Next, it is divided into three parts: Part One: General Methods and Strategies Part Two: Stereoselective Synthesis by Bond Formation including C-C bond formation C-H bond formation C-O bond formation C-N bond formation Other C-heteroatom formation and other bond formation Part Three: Methods of Analysis and Chiral Separation References in every chapter serve as a gateway to the literature in the field. With this publication as their guide, chemists involved in the stereoselective synthesis of drugs and natural products now have a single, expertly edited source for all the methods they need.
Call Number: (Electronic Resource)Publication Date: 2013
Systematic Bacteriology
Bacteriologists from all levels of expertise and within all specialties rely on this Manual as one of the most comprehensive and authoritative works. Since publication of the first edition of the Systematics, the field has undergone revolutionary changes, leading to a phylogenetic classification of prokaryotes based on sequencing of the small ribosomal subunit. The list of validly named species has more than doubled since publication of the first edition, and descriptions of over 2000 new and realigned species are included in this new edition along with more in-depth ecological information about individual taxa and extensive introductory essays by leading authorities in the field.
Call Number: QR81 .B46 2001 (Print and Electronic Resource)Publication Date: 2001
The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals
The seminal reference on the care of laboratory and captive animals, The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals is a must-have for anyone working in this field. The UFAW Handbook has been the definitive text since 1947. Written for an international audience, it contains contributions from experts from around the world. The book focuses on best practice principles throughout, providing comprehensive coverage, with all chapters being peer reviewed by anonymous referees.
Call Number: (Electronic Resource)Publication Date: 2010
